TRE-515 (CAS No. 2107280-55-5) is a potent and selective deoxycytidine kinase (dCK) inhibitor with a novel mechanism of action. By inhibiting the nucleoside salvage pathway, TRE-515 exhibits excellent selectivity, favorable pharmacokinetic characteristics, and promising antitumor efficacy, making it an attractive small-molecule candidate for cancer metabolism-targeted drug development.